BRG1 LOSS ATTENUATES ABERRANT WNT-SIGNALLING AND PREVENTS WNT-DEPENDENT TUMOURIGENESIS IN THE MURINE SMALL INTESTINE.

Brg1 loss attenuates aberrant wnt-signalling and prevents wnt-dependent tumourigenesis in the murine small intestine.

Tumourigenesis within the intestine is potently driven by deregulation of the Wnt pathway, a process epigenetically regulated by the chromatin remodelling factor Brg1.We aimed to investigate this interdependency in an in vivo setting and assess the viability of Brg1 as a potential therapeutic target.Using a Mystery Minis range of transgenic approac

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Applying the Capability, Opportunity, and Motivation Behaviour Model (COM-B) to Guide the Development of Interventions to Improve Early Detection of Atrial Fibrillation

Objective: The primary objective of this study is to use the Capability, Opportunity, and Motivation Behaviour (COM-B) model to identify potential strategies aimed at improving the early detection of atrial fibrillation (AF) in the general population.Methods: We undertook a review of the literature to identify factors associated with participation

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Effect of physiochemical parameters on yield and biological efficiency of Volvariella volvacea cultivated on empty fruit bunch pellets

Background: Volvariella volvacea is a highly nutritious edible mushroom grown mainly in Southeast Asian countries.However, the low yield of V.volvacea has discouraged farmers from engaging in its production.Objective: The study was conducted to observe the improvement of V.volvacea yield depending on various physiochemical parameters of V.volvacea

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